Fusion protein linkers: Property, design and functionality
نویسندگان
چکیده
منابع مشابه
Design and characterization of structured protein linkers with differing flexibilities
Engineered fusion proteins containing two or more functional polypeptides joined by a peptide or protein linker are important for many fields of biological research. The separation distance between functional units can impact epitope access and the ability to bind with avidity; thus the availability of a variety of linkers with different lengths and degrees of rigidity would be valuable for pro...
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ژورنال
عنوان ژورنال: Advanced Drug Delivery Reviews
سال: 2013
ISSN: 0169-409X
DOI: 10.1016/j.addr.2012.09.039